Mission
To catalyze early innovation to deliver life-changing medicines globally to patients through unparalleled R&D efficiency and agile partnerships.
We define the success of our work at OTR Therapeutics by the impact we make for our patients, partners and employees.
Scientific breakthrough:
Delivering therapies with meaningful clinical differentiation and impact.
Operational excellence:
Setting new benchmarks for efficiency in drug development.
Global collaboration:
Creating a collaborative network where science thrives beyond borders.
Our Team
Zhui Chen, Ph.D.
Founder & Chief Executive Officer
Shannon Chuai, Ph.D.
Co-Founder & Chief Operating Officer
Yuan Shi, Ph.D.
Co-Founder & Chief Scientific Officer

Copyright © 2025 OTR Therapeutics. All rights reserved.

Terms and Conditions Privacy Policy

Zhui Chen, Ph.D.
Founder & Chief Executive Officer

Dr. Zhui Chen is the Founder and CEO of OTR Therapeutics. Prior to founding OTR, he co-founded Abbisko Therapeutics, where he served as Board Director and Co-Chief Scientific Officer, leading R&D, business development, and strategic initiatives that guided the company from inception to successful public listing. Earlier in his career, Dr. Chen held senior roles at Johnson & Johnson’s Shanghai Innovation Center, where he led oncology discovery and translational research. He also worked at Novartis Institute of Biomedical Research and Abbott Laboratories, driving discovery and translational efforts across oncology and other therapeutic areas. Dr. Chen holds a Ph.D. in Biochemistry from Duke University, completed postdoctoral training at UT Southwestern, and earned his B.S. from the University of Texas at Austin following undergraduate studies at Peking University.

Shannon Chuai, Ph.D.
Co-Founder & Chief Operating Officer

Dr. Shannon Chuai is the Co-Founder and COO of OTR Therapeutics. With over 20 years of experience spanning pharmaceuticals, diagnostics, and investment, she brings deep expertise in scaling biotech operations, securing financing, and driving cross-functional collaboration in fast-paced growing environments. Previously, she managed healthcare investments at Legend Star and co-founded Burning Rock Biotech (NASDAQ: BNR), where she served as CTO and COO. At Burning Rock, she led the development of China’s first NGS-based oncology diagnostics platform, achieving the country’s first Class III IVD approval for an NGS panel and an FDA breakthrough designation for a multi-cancer early detection assay. Earlier in her career, Dr. Chuai held R&D roles at Novartis, University of Pennsylvania, and Memorial Sloan-Kettering Cancer Center, focusing on data-driven drug discovery. Dr. Chuai holds a Ph.D. in Biostatistics from University of Pennsylvania, an M.S. in Statistics from Texas A&M University, and a B.S. in Biochemistry from NanKai University.

Yuan Shi, Ph.D.
Co-Founder & Chief Scientific Officer

Dr. Yuan Shi is the Co-Founder and CSO of OTR Therapeutics. He brings broad experience across drug discovery, clinical portfolio management, scientific partnering and biotech entrepreneurship. Previously, he co-founded INF Technology, establishing an AI-driven drug discovery unit and leading external alliances. During his 11-year tenure at Eli Lilly, he served as COO of Clinical Portfolio Management, overseeing development strategies for small molecule and RNA-based therapies. He also served as Director of Discovery Chemistry, advancing multiple drug candidates into clinical stage across oncology, metabolism, and neurodegeneration. He also supported Lilly’s business development and forged regional partnerships. Dr. Shi earned his Ph.D. in Chemistry from the Cornell-Rockefeller-MSKCC Tri-Institutional Program and B.S from University of Science and Technology of China.

Privacy Policy

Introduction

OTR Therapeutics (Shanghai) Co., Ltd. (hereinafter referred to as “OTR”, or “we”) respects the privacy of visitors (“You” or “Users) to our website www.otr-tx.com (“Website”), and therefore we establish this Privacy Policy (this “Policy”) pursuant to the applicable laws and regulations of China on the protection of personal information. This Policy applies to this Website and the services you may use on this Website. Please read carefully and make sure that you fully understand this Policy. If you do not agree to this Policy, please do not use this Website.

Information Collection

When you interact with us through this Website, we may collect your personal information to perform and respond to your requests to us. Under this Policy, “Personal Information” means any information by which you can be identified, such as your name, birthday, e-mail address, postal address, telephone number, or education background and professional experience (such as to submit resume online). It is entirely your choice to provide us your Personal Information, and OTR only collects the information you provide to us. According to this Policy, you will be deemed to have agreed to our use of your Personal Information when you visit this Website and provide us with your Personal Information.

Information Use

We will use such Personal Information solely for the purposes of maintaining this website, assisting you to register to acquire relevant services you may need, and responding to your questions and requests for information. 

When we want to use Personal Information for other purposes not specified in this policy, we will seek your consent in advance. When we want to use the Personal Information collected for a specific purpose for other purposes, we will ask for your consent in advance.

Information Disclosures and Sharing

Except as provided below, we will not share your Personal Information with third parties unless you have consented to the disclosure.

sometimes we will ask some other companies or persons for service such as system technical support. To provide this kind of service, they may have access to your Personal Information but will not use the Personal Information for any other purpose.

We may share Personal Information to respond to duly authorized subpoenas or other lawful information requests of governmental authorities, including to meet national security or law enforcement requirements, to provide Internet security, or where required by law.

According to relevant laws and regulations, we may collect and use some necessary personal information without obtaining your authorized consent in the following situations:

(1)It is necessary for the conclusion and performance of any contract to which the individual is a party;

(2) It is necessary for the performance of statutory duties or obligations;

(3) It is necessary to respond to public health emergencies, or to protect the life, health and property safety of natural persons in emergency situations;

(4) Processing personal information that is publicly disclosed by individuals or others legally to a reasonable extent in accordance with the provisions of the Personal Information Protection Law;

(5) Other circumstances provided by laws and regulations.

Security Measures

In accordance with relevant national standards, we implement security precaution measures that satisfies industrial standards to protect your Personal Information. Nevertheless, you shall remain responsible to make sure that your computer is sufficiently secured and protected from leaking your Personal Information.

Third Party Links

This Policy applies only to this Website. This Website may contain links to other Websites ("Third-Party Websites") that are not operated or controlled by OTR. The policies and procedures described herein do not apply to Third-Party Websites. Links to this Website do not imply that we endorse or have reviewed Third-Party Websites. We encourage you to contact these sites directly to obtain their privacy policy.

Minor’s Privacy

Our service does not address anyone under the age of fourteen (14). We do not knowingly collect personally identifiable information from minors under fourteen (14). In the case we discover that a minor under fourteen (14) has provided us with personal information, we immediately delete this from our servers. If you are a parent or guardian and you are aware that your child has provided us with personal information, please contact us so that we will be able to take necessary steps.

Miscellaneous

This Policy is made and effective on June 11, 2025, which is the latest version.

OTR reserves the right to modify this Policy at any time by notifying Users, via the Website, of a new or updated Policy, and you can review the most up-to-date version on this Website.

Contact Us

If you have any questions about this Policy, please contact us at info@otr-tx.com.


Terms and Conditions

This website www.otr-tx.com (“Website”) is developed and operated by OTR Therapeutics (Shanghai) Co., Ltd. (“OTR”). Any entity or individual is advised to read this Terms and Conditions carefully before access, browse or use this website. Do not access this Website if you do not consent to the terms herein. By your continued accessing, browsing, or using this Website, you will be deemed to have understood and fully agreed to be subject to this Terms and Conditions and abide by the laws and regulations applicable to this Terms and Conditions.

You understand and agree that we may change this Terms and Conditions at any time without prior notice. Please review this Terms and Conditions periodically to make sure that you are aware of contents in the most up-to-date version. If you do not accept any revision to this Terms and Conditions, please stop visiting, browsing, and otherwise using the Website.

Your access to and use of this Website is also governed by the Privacy Policy of OTR, which is hereby incorporated by reference.

Prohibitions

When using this Website, you shall (a) not infringe lawful interests of OTR or other third parties, (b) not interfere with or attempt to interfere with, by any means whatsoever, normal operation of this Website, (c) not to attempt to decrypt, decompile, disassemble or reverse engineer any software contained on or constitutes this Website, (d) not to attempt discover the source code of this Website by any other means, (e)not to delete or change any published material by OTR or any other person or entity on this Website, or (f) not to include or link to any material or information provided on this Website within the web framework.

Content and Intellectual Property

All contents on this Website and their copyrights, including but not limited to data, texts, logos, graphics, audios, animations, records, videos, interface design, or page layout framework belong to OTR, unless otherwise indicated or be made known expressly that they belong to a third party. This website and all relevant contents are protected under the laws and regulations of China and applicable international laws and regulations on copyrights. Users are not allowed to use, reproduce or reuse such content for any purposes. OTR reserves all rights that we do not explicitly grant to users in this Terms.

All trademarks, service marks, trade names, logos, and icons used and displayed on this Website are proprietary to OTR and its affiliates. Other company, product, and service names on this Website may be trademarks or service marks owned by third parties ("third-party trademarks", together with trademarks owned by OTR collectively referred to as "Trademark"). Nothing in this Website or this Terms and Conditions shall be construed as granting, by implication, estoppel or otherwise, any license or right to use any Trademarks displayed on this Website without the prior written consent of OTR or other relevant trademark owners. Trademarks may not be used to undermine the image, product, or service of OTR or any third party, or to damage the goodwill represented by the Trademark in any way (as judged by reasonable business rules).

Disclaimers

TO THE FULL EXTENT PERMISSIBLE BY LAW, OFFICIALS, DIRECTORS, EMPLOYEES, AGENTS, SUPPLIERS OR LICENSORS OF EACH OF OTR AND ITS AFFILIATES (COLLECTIVELLY REFERRED TO AS “OTR PARTIES”) MAKE NO WARRANTIES, STATEMENTS OR REPRESENTATIONS, EXPRESS OR IMPLIED, ON ANY CONTENT ON THIS WEBSITE (INCLUDING BUT NOT LIMITED TO, PROMPTNESS, GENERALITY, PRECISION, RELIABILITY, COMPLETENESS OF SUCH CONTENT FOR A PARTICULAR PURPOSE, OR ACCURATENESS OR CREDIBILITY OF ANY INFORMATION GAINED FROM THIS WEBSITE). OTR MAKES NO COMMITMENT TO UPDATE ALL OR PART OF THE CONTENTS ON THIS WEBSITE IN A TIMELY MANNER. OTR RESERVES THE RIGHT TO CORRECT, MODIFY OR CEASE TO PUBLISH ALL OR ANY PART OF THE CONTENTS ON THIS WEBSITE WITHOUT NOTICE TO ANY PARTY AND SHALL NOT UNDERTAKE ANY LIABILITIES THEREOF. YOU ASSUME TOTAL RESPONSIBILITY FOR ALL THE RISKS ARISING FROM YOUR ACCEPTANCE OF ANY SUGGESTION, VIEW, STATEMENT, OR INFORMATION ON THIS WEBSITE, IN WHICH CASE OTR DISCLAIMS ANY AND ALL LIABILITY.

FOR THE USE OF THIS WEBSITE OR ANY INFORMATION OBTAINED OR DOWNLOADED FROM THIS WEBSITE, YOU SHALL AGREE THAT YOU WILL, AT YOUR OWN RISK, DECIDE WHETHER TO USE THEM. OTR, ITS LICENSOR, SUPPLIERS OR ANY THIRD PARTY MENTIONED ON THIS WEBSITE SHALL NOT UNDERTAKE ANY LIABILITY FOR ANY LOSS RESULTING FROM THE USE OR UNAVAILABILITY OF THIS WEBSITE, OR ANY MALFUNCTION, COMPUTER VIRUS OR LOSS OF DATA OCCURRED IN OPERATION OR TRANSITION.

According to relevant laws and regulations, we may collect and use some necessary personal information without obtaining your authorized consent in the following situations:

Indemnification

You agree to hold, indemnify, and prevent OTR and OTR Parties from being liable for any claims, damages, costs, liability, or expense resulting from or allegedly resulting from your breach of this Terms and Conditions, including but not limited to direct losses such as administrative penalties or damages, and indirect losses such as loss of goodwill, settlement payments, reasonable attorney fees and accounting fees. In the event of such claims, damages, costs, liability, or expense, OTR will notify you. OTR has the right to exclusive defense and control of any matter for indemnification under this section. In this case, you agree to provide OTR with assistance as OTR may reasonably request in defending such matters.

Termination of use

OTR reserves the right, in its sole discretion, to limit, suspend, or terminate this Terms and Conditions and your rights to use all or any part of this Website or Content at any time and for any reason, without notice or liability. OTR reserves the right to change, suspend or terminate all or any part of this Website or Content at any time without notice or liability.

Medical Information

Nothing on this Website shall be construed as providing any kind of medical advice or recommendation and shall not be relied on for any decision or action. Specific medical advice shall always be sought from a qualified medical practitioner.

Third Party Links

This Website contains links to third party websites. OTR shall not be deemed to have agreed to any of its contents by providing such links. Neither does OTR accept any responsibility for the availability or the contents of such websites or any liability or damage resulting from the use of such contents. Links to such websites are provided to users of this website merely for the sake of convenience. access such websites at their own risks.

Governing law

Any dispute in connection with this Website or this Terms and Conditions shall be governed by laws of the People’s Republic of China, excluding the Hong Kong, Macau, and Taiwan.

Dispute Resolution

In the event of any dispute, controversy or claim arising out of or relating to these Terms of Use or your use of the Website, Content or Services, you shall attempt in the first instance to resolve such dispute through friendly consultations.

In the event such dispute is not resolved through consultations within thirty (30) days after the date such consultations were first requested in writing, then you or we may submit the dispute for arbitration in Shanghai before the Shanghai International Economic and Trade Arbitration Commission(“SHIAC”) in accordance with SHIAC Arbitration Rules then in force. The arbitral award shall be final and binding, and shall be legally binding on both parties.

Miscellaneous

If the clauses of this Terms shall be partially invalid or unenforceable for any reason, the remaining clauses shall remain in force and shall remain binding on the Parties. If a provision states that OTR has a particular right in a particular circumstance, this does not mean that that right is the only right OTR may exercise in that particular circumstance, or that that provision cancels, voids or invalidates any other provisions that deal with the same circumstance or subject-matter.

The latest version of this Terms and Conditions is made and effective on June 11, 2025.